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DC Field | Value | Language |
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dc.contributor.author | Bajaj, J. S. | - |
dc.contributor.author | Choudhury, A. | - |
dc.contributor.author | Kumaran, V. | - |
dc.contributor.author | Wong, F. | - |
dc.contributor.author | Seto, W. K. | - |
dc.contributor.author | Alvares-Da-Silva, M. R. | - |
dc.contributor.author | Desalgn, H. | - |
dc.contributor.author | Hayes, P. C. | - |
dc.contributor.author | Idilman, R. | - |
dc.contributor.author | Topazian, M. | - |
dc.contributor.author | Torre, A. | - |
dc.contributor.author | Xie, Q. | - |
dc.contributor.author | George, Jacob | - |
dc.contributor.author | Kamath, P. S. | - |
dc.date.accessioned | 2024-05-16T06:00:57Z | - |
dc.date.available | 2024-05-16T06:00:57Z | - |
dc.date.issued | 2024 | - |
dc.identifier.citation | American Journal of Transplantation 24(5):733-742, 2024 | - |
dc.identifier.uri | https://wslhd.intersearch.com.au/wslhdjspui/handle/1/9652 | - |
dc.description.abstract | Decompensated cirrhosis and hepatocellular cancer are major risk factors for mortality worldwide. Liver transplantation (LT), both live-donor LT or deceased-donor LT, are lifesaving, but there are several barriers toward equitable access. These barriers are exacerbated in the setting of critical illness or acute-on-chronic liver failure. Rates of LT vary widely worldwide but are lowest in lower-income countries owing to lack of resources, infrastructure, late disease presentation, and limited donor awareness. A recent experience by the Chronic Liver Disease Evolution and Registry for Events and Decompensation consortium defined these barriers toward LT as critical in determining overall survival in hospitalized cirrhosis patients. A major focus should be on appropriate, affordable, and early cirrhosis and hepatocellular cancer care to prevent the need for LT. Live-donor LT is predominant across Asian countries, whereas deceased-donor LT is more common in Western countries; both approaches have unique challenges that add to the access disparities. There are many challenges toward equitable access but uniform definitions of acute-on-chronic liver failure, improving transplant expertise, enhancing availability of resources and encouraging knowledge between centers, and preventing disease progression are critical to reduce LT disparities. | - |
dc.title | Geographic disparities in access to liver transplant for advanced cirrhosis: Time to ring the alarm! | - |
dc.type | Journal Article | - |
dc.identifier.doi | https://dx.doi.org/10.1016/j.ajt.2024.02.018 | - |
dc.subject.keywords | Liver Transplantation | - |
dc.subject.keywords | Liver Cirrhosis | - |
dc.subject.keywords | Health Services Accessibility | - |
dc.subject.keywords | Healthcare Disparities | - |
dc.identifier.journaltitle | American Journal of Transplantation | - |
dc.identifier.department | Storr Liver Centre | - |
dc.contributor.wslhd | George, Jacob | - |
dc.type.studyortrial | Review | - |
dc.identifier.pmid | 38387623 | - |
dc.identifier.facility | Westmead | - |
Appears in Collections: | Westmead Hospital 2019 - 2024 |
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